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Entpd5 (NM_001026214) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR206800L3V
- LentiORF®
-
Lenti ORF particles, Entpd5 (Myc-DDK-tagged) - Mouse ectonucleoside triphosphate diphosphohydrolase 5 (Entpd5), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Entpd5 (NM_001026214) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AI196558; AI987697; Cd39l4; ER-UDPase; mNTPase; NTPDase-5; NTPDase5; Pcph |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001026214 |
| ORF Size | 1284 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR206800).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001026214.1 |
| RefSeq Size | 4987 bp |
| RefSeq ORF | 1284 bp |
| Locus ID | 12499 |
| Gene Summary | Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.[UniProtKB/Swiss-Prot Function] |
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