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E2f1 (NM_007891) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR206856L3V
- LentiORF®
-
Lenti ORF particles, E2f1 (Myc-DDK-tagged) - Mouse E2F transcription factor 1 (E2f1), 200ul, >10^7 TU/mL
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CNY 7,410.00
货期*
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规格
| Cited in 3 publications. |
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经常一起买 (2)
Specifications
| Product Data | |
| Product Name | E2f1 (NM_007891) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | E2F-1; mKIAA4009; Tg(Wnt1-cre)2Sor |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_007891 |
| ORF Size | 1290 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR206856).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_007891.1 |
| RefSeq Size | 2469 bp |
| RefSeq ORF | 1293 bp |
| Locus ID | 13555 |
| Gene Summary | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:11672531, PubMed:20176812). Positively regulates transcription of RRP1B (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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E2F1-dependent miR-421 regulates mitochondrial fragmentation and myocardial infarction by targeting Pink1.
,null,
Nature communications
,PubMed ID 26184432
[E2f1]
|
|
E2F1-regulated miR-30b suppresses Cyclophilin D and protects heart from ischemia/reperfusion injury and necrotic cell death
,null,
Cell Death and Differentiation
,PubMed ID 25301066
[E2f1]
|
|
Autophagic program is regulated by miR-325
,null,
Cell Death and Differentiation
,PubMed ID 24531537
[E2f1]
|
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