Dnaja3 (NM_001135112) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR207237L3V
- LentiORF®
Lenti ORF particles, Dnaja3 (Myc-DDK-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily A, member 3 (Dnaja3), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
Product Data | |
Product Name | Dnaja3 (NM_001135112) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 1200003J13Rik; 1810053A11Rik; C81173; Tid-1; Tid1l |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001135112 |
ORF Size | 1359 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR207237).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001135112.1, NP_001128584.1 |
RefSeq Size | 2549 bp |
RefSeq ORF | 1362 bp |
Locus ID | 83945 |
Gene Summary | Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity (By similarity). Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.[UniProtKB/Swiss-Prot Function] |
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