Dkc1 (NM_001030307) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR208185L4V
- LentiORF®
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Lenti ORF particles, Dkc1 (GFP-tagged) - Mouse dyskeratosis congenita 1, dyskerin homolog (human) (Dkc1), 200ul, >10^7 TU/mL
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CNY 10,735.00
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Specifications
Product Data | |
Product Name | Dkc1 (NM_001030307) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | BC068171 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001030307 |
ORF Size | 1527 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR208185).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001030307.2, NP_001025478.1 |
RefSeq Size | 2803 bp |
RefSeq ORF | 1530 bp |
Locus ID | 245474 |
Gene Summary | Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA (PubMed:12522253, PubMed:15240872). This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs (PubMed:12522253, PubMed:15240872). Required for ribosome biogenesis and telomere maintenance (By similarity). Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme (By similarity).[UniProtKB/Swiss-Prot Function] |
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