Oma1 (NM_025909) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR208350L4V
- LentiORF®
-
Lenti ORF particles, Oma1 (GFP-tagged) - Mouse OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (Oma1), 200ul, >10^7 TU/mL
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CNY 10,925.00
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Specifications
Product Data | |
Product Name | Oma1 (NM_025909) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 2010001O09Rik; MPRP-1; ZMPOMA1 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_025909 |
ORF Size | 1566 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR208350).
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OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_025909.1 |
RefSeq Size | 1866 bp |
RefSeq ORF | 1566 bp |
Locus ID | 67013 |
Gene Summary | Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion (PubMed:22433842, PubMed:24616225, PubMed:26785494). May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.[UniProtKB/Swiss-Prot Function] |
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