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Nae1 (NM_144931) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR208551L3V
- LentiORF®
-
Lenti ORF particles, Nae1 (Myc-DDK-tagged) - Mouse NEDD8 activating enzyme E1 subunit 1 (Nae1), 200ul, >10^7 TU/mL
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CNY 9,880.00
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Specifications
| Product Data | |
| Product Name | Nae1 (NM_144931) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 59kDa; Appbp1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_144931 |
| ORF Size | 1605 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR208551).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_144931.1 |
| RefSeq Size | 1808 bp |
| RefSeq ORF | 1605 bp |
| Locus ID | 234664 |
| Gene Summary | Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation (By similarity).[UniProtKB/Swiss-Prot Function] |
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