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Zfp451 (BC019546) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR208860L3V
- LentiORF®
-
Lenti ORF particles, Zfp451 (Myc-DDK-tagged) - Mouse zinc finger protein 451 (cDNA clone MGC:28438 IMAGE:4038791), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | Zfp451 (BC019546) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 4930515K21Rik; 4933435G09Rik; AI596398; COASTER; Kiaa0576-hp; mKIAA1702; Znf451 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC019546 |
| ORF Size | 1677 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR208860).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC019546, AAH19546 |
| RefSeq Size | 1928 bp |
| RefSeq ORF | 1679 bp |
| Locus ID | 98403 |
| Gene Summary | E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins. Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation. Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11'. Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300-mediated acetylation of histone H3 at 'Lys-9'. Plays a role in regulating the transcription of AR targets (By similarity).[UniProtKB/Swiss-Prot Function] |
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