Prc1 (NM_145150) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR209337L4V
- LentiORF®
Lenti ORF particles, Prc1 (GFP-tagged) - Mouse protein regulator of cytokinesis 1 (Prc1), 200ul, >10^7 TU/mL
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CNY 11,970.00
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Specifications
Product Data | |
Product Name | Prc1 (NM_145150) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | D7Ertd348e |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_145150 |
ORF Size | 1812 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR209337).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_145150.1, NP_660132.1 |
RefSeq Size | 3049 bp |
RefSeq ORF | 1821 bp |
Locus ID | 233406 |
Gene Summary | Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression.[UniProtKB/Swiss-Prot Function] |
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