Nxf1 (NM_016813) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR209464L3V
- LentiORF®
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Lenti ORF particles, Nxf1 (Myc-DDK-tagged) - Mouse nuclear RNA export factor 1 homolog (S. cerevisiae) (Nxf1), 200ul, >10^7 TU/mL
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CNY 10,830.00
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规格
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Specifications
Product Data | |
Product Name | Nxf1 (NM_016813) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | Mex67; Mvb1; Tap |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_016813 |
ORF Size | 1857 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR209464).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_016813.2, NP_058093.2 |
RefSeq Size | 2312 bp |
RefSeq ORF | 1857 bp |
Locus ID | 53319 |
Gene Summary | Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export. Also involved in nuclear export of m6A-containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export.[UniProtKB/Swiss-Prot Function] |
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