United States
Germany
Japan
United Kingdom
China
Amfr (NM_011787) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR209712L4V
- LentiORF®
-
Lenti ORF particles, Amfr (GFP-tagged) - Mouse autocrine motility factor receptor (Amfr), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 12,350.00
货期*
详询
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Product Name | Amfr (NM_011787) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | gp78 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_011787 |
| ORF Size | 1917 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR209712).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_011787.2, NP_035917.2 |
| RefSeq Size | 3694 bp |
| RefSeq ORF | 1920 bp |
| Locus ID | 23802 |
| Gene Summary | E3 ubiquitin-protein ligase that mediates the polyubiquitination of a number of proteins such as CD3D, CYP3A4, CFTR and APOB for proteasomal degradation. Component of a VCP/p97-AMFR/gp78 complex that participates in the final step of endoplasmic reticulum-associated degradation (ERAD). The VCP/p97-AMFR/gp78 complex is involved in the sterol-accelerated ERAD degradation of HMGCR through binding to the HMGCR-INSIG complex at the ER membrane and initiating ubiquitination of HMGCR. The ubiquitinated HMGCR is then released from the ER by the complex into the cytosol for subsequent destruction. Also regulates ERAD through the ubiquitination of UBL4A a component of the BAG6/BAT3 complex. Also acts as a scaffold protein to assemble a complex that couples ubiquitination, retranslocation and deglycosylation. Mediates tumor invasion and metastasis (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
