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Large2 (NM_172670) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR210059L3V
- LentiORF®
-
Lenti ORF particles, Gyltl1b (Myc-DDK-tagged) - Mouse glycosyltransferase-like 1B (Gyltl1b), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 11,685.00
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Specifications
| Product Data | |
| Product Name | Large2 (NM_172670) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 5730485C17Rik; AI891893; Gyltl1b; Largel; mKIAA4105 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_172670 |
| ORF Size | 2070 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR210059).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_172670.3, NP_766258.2 |
| RefSeq Size | 2424 bp |
| RefSeq ORF | 2073 bp |
| Locus ID | 228366 |
| Gene Summary | Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide. Has a higher activity toward alpha-dystroglycan than LARGE (PubMed:15958417).[UniProtKB/Swiss-Prot Function] |
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