Pcca (NM_144844) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR210302L4V

  • LentiORF®

Lenti ORF particles, Pcca (GFP-tagged) - Mouse propionyl-Coenzyme A carboxylase, alpha polypeptide (Pcca), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 13,395.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Pcca (NM_144844) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms C79630
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_144844
ORF Size 2172 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR210302).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_144844.2, NP_659093.2
RefSeq Size 2603 bp
RefSeq ORF 2175 bp
Locus ID 110821
Gene Summary This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites. Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (By similarity). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)-ethylmalonyl-CoA (By similarity). Other alternative minor substrates include (2E)-butenoyl-CoA/crotonoyl-CoA (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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