Pcca (NM_144844) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR210302L4V
- LentiORF®
Lenti ORF particles, Pcca (GFP-tagged) - Mouse propionyl-Coenzyme A carboxylase, alpha polypeptide (Pcca), 200ul, >10^7 TU/mL
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CNY 13,395.00
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Specifications
Product Data | |
Product Name | Pcca (NM_144844) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | C79630 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_144844 |
ORF Size | 2172 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR210302).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_144844.2, NP_659093.2 |
RefSeq Size | 2603 bp |
RefSeq ORF | 2175 bp |
Locus ID | 110821 |
Gene Summary | This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites. Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (By similarity). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)-ethylmalonyl-CoA (By similarity). Other alternative minor substrates include (2E)-butenoyl-CoA/crotonoyl-CoA (By similarity).[UniProtKB/Swiss-Prot Function] |
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