Wwp1 (BC026829) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR210655L3V

  • LentiORF®

Lenti ORF particles, Wwp1 (Myc-DDK-tagged) - Mouse WW domain containing E3 ubiquitin protein ligase 1 (cDNA clone MGC:28572 IMAGE:4209397), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 11,875.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Wwp1 (BC026829) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms AIP5, SDRP1, Tiul1
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN BC026829
ORF Size 2361 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR210655).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq BC026829.1
RefSeq Size 3107 bp
RefSeq ORF 2363 bp
Locus ID 107568
Gene Summary E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF (By similarity). Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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