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Wwp1 (BC026829) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR210655L3V
- LentiORF®
-
Lenti ORF particles, Wwp1 (Myc-DDK-tagged) - Mouse WW domain containing E3 ubiquitin protein ligase 1 (cDNA clone MGC:28572 IMAGE:4209397), 200ul, >10^7 TU/mL
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CNY 11,875.00
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Specifications
| Product Data | |
| Product Name | Wwp1 (BC026829) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AIP5, SDRP1, Tiul1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC026829 |
| ORF Size | 2361 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR210655).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC026829.1 |
| RefSeq Size | 3107 bp |
| RefSeq ORF | 2363 bp |
| Locus ID | 107568 |
| Gene Summary | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF (By similarity). Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7.[UniProtKB/Swiss-Prot Function] |
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