Slc4a10 (NM_033552) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR211614L4V
- LentiORF®
Lenti ORF particles, Slc4a10 (GFP-tagged) - Mouse solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 (Slc4a10), 200ul, >10^7 TU/mL
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CNY 18,050.00
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Specifications
Product Data | |
Product Name | Slc4a10 (NM_033552) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | mKIAA4136; NCBE |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_033552 |
ORF Size | 3264 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR211614).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_033552.3, NP_291030.2 |
RefSeq Size | 5463 bp |
RefSeq ORF | 3267 bp |
Locus ID | 94229 |
Gene Summary | Sodium/bicarbonate cotransporter which plays an important role in regulating intracellular pH (PubMed:10993873, PubMed:20566632). Has been shown to act as a sodium/bicarbonate cotransporter in exchange for intracellular chloride (PubMed:10993873, PubMed:20566632). Has also been shown to act as a sodium/biocarbonate cotransporter which is not responsible for net efflux of chloride, with the observed chloride efflux being due to chloride self-exchange (By similarity). Controls neuronal pH and may contribute to the secretion of cerebrospinal fluid (PubMed:18165320). Reduces the excitability of CA1 pyramidal neurons and modulates short-term synaptic plasticity (PubMed:26136660). Required in retinal cells to maintain normal pH which is necessary for normal vision (PubMed:23056253). In the kidney, likely to mediate bicarbonate reclamation in the apical membrane of the proximal tubules (By similarity).[UniProtKB/Swiss-Prot Function] |
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