Cilp (NM_173385) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR211772L3V

  • LentiORF®

Lenti ORF particles, Cilp (Myc-DDK-tagged) - Mouse cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (Cilp), 200ul, >10^7 TU/mL



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CNY 18,050.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Cilp (NM_173385) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 9830114D16; C130036G17Rik
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_173385
ORF Size 3552 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR211772).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_173385.2
RefSeq Size 4153 bp
RefSeq ORF 3753 bp
Locus ID 214425
Gene Summary Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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