Cilp (NM_173385) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR211772L4V
- LentiORF®
Lenti ORF particles, Cilp (GFP-tagged) - Mouse cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (Cilp), 200ul, >10^7 TU/mL
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CNY 20,045.00
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Specifications
Product Data | |
Product Name | Cilp (NM_173385) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 9830114D16; C130036G17Rik |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_173385 |
ORF Size | 3552 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR211772).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_173385.2 |
RefSeq Size | 4153 bp |
RefSeq ORF | 3753 bp |
Locus ID | 214425 |
Gene Summary | Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage (By similarity).[UniProtKB/Swiss-Prot Function] |
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