Calcoco2 (NM_029755) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR216075L4V
- LentiORF®
-
Lenti ORF particles, Calcoco2 (GFP-tagged) - Mouse calcium binding and coiled-coil domain 2 (Calcoco2), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,360.00
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规格
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Specifications
Product Data | |
Product Name | Calcoco2 (NM_029755) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 2410154J16Rik; C77254; Ndp52; Ndp52l1 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_029755 |
ORF Size | 930 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR216075).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_029755.3, NP_084031.2 |
RefSeq Size | 1556 bp |
RefSeq ORF | 933 bp |
Locus ID | 76815 |
Gene Summary | Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation (By similarity). Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (By similarity). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation (By similarity). Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C (By similarity). May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion (By similarity).[UniProtKB/Swiss-Prot Function] |
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