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Rnf7 (NM_011279) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR220386L3V
- LentiORF®
-
Lenti ORF particles, Rnf7 (Myc-DDK-tagged) - Mouse ring finger protein 7 (Rnf7), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Rnf7 (NM_011279) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Rbx2; SAG |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_011279 |
| ORF Size | 342 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR220386).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_011279.2, NP_035409.1 |
| RefSeq Size | 1132 bp |
| RefSeq ORF | 342 bp |
| Locus ID | 19823 |
| Gene Summary | Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription (By similarity). CRLs complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins, ARIH1 mediating addition of the first ubiquitin on CRLs targets (By similarity). Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents (By similarity).[UniProtKB/Swiss-Prot Function] |
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