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Sp100 (NM_013673) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR220765L3V
- LentiORF®
-
Lenti ORF particles, Sp100 (Myc-DDK-tagged) - Mouse nuclear antigen Sp100 (Sp100), 200ul, >10^7 TU/mL
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CNY 10,545.00
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Specifications
| Product Data | |
| Product Name | Sp100 (NM_013673) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | A430075G10Rik |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_013673 |
| ORF Size | 1773 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR220765).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_013673.3, NP_038701.2 |
| RefSeq Size | 2158 bp |
| RefSeq ORF | 1776 bp |
| Locus ID | 20684 |
| Gene Summary | Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes including cell growth, differentiation and apoptosis. Functions as a transcriptional coactivator of ETS1 and ETS2. Under certain conditions, it may also act as a corepressor of ETS1 preventing its binding to DNA. Through the regulation of ETS1 it may play a role in angiogenesis, controlling endothelial cell motility and invasion. Through interaction with the MRN complex it may be involved in the regulation of telomeres lengthening. May also regulate TP53-mediated transcription and through CASP8AP2, regulate FAS-mediated apoptosis. May also play a role in infection by viruses through mechanisms that may involve chromatin and/or transcriptional regulation (By similarity).[UniProtKB/Swiss-Prot Function] |
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