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Atf6 (NM_001081304) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR221667L3V
- LentiORF®
-
Lenti ORF particles, Atf6 (Myc-DDK-tagged) - Mouse activating transcription factor 6 (Atf6), 200ul, >10^7 TU/mL
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CNY 11,305.00
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Specifications
| Product Data | |
| Product Name | Atf6 (NM_001081304) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 9130025P16Rik; 9630036G24; AA789574; Atf6alpha; ESTM49 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001081304 |
| ORF Size | 1968 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR221667).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001081304.1 |
| RefSeq Size | 7463 bp |
| RefSeq ORF | 1971 bp |
| Locus ID | 226641 |
| Gene Summary | Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina (By similarity).[UniProtKB/Swiss-Prot Function] |
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