Ripk3 (NM_019955) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR222511L4V

  • LentiORF®

Lenti ORF particles, Ripk3 (GFP-tagged) - Mouse receptor-interacting serine-threonine kinase 3 (Ripk3), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 10,450.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Ripk3 (NM_019955) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 2610528K09Rik; AW107945; Rip3
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_019955
ORF Size 1458 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR222511).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_019955.2, NP_064339.2
RefSeq Size 1899 bp
RefSeq ORF 1461 bp
Locus ID 56532
Gene Summary Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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