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Trim25 (NM_009546) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR223266L4V
- LentiORF®
-
Lenti ORF particles, Trim25 (GFP-tagged) - Mouse tripartite motif-containing 25 (Trim25), 200ul, >10^7 TU/mL
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CNY 12,255.00
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规格
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Specifications
| Product Data | |
| Product Name | Trim25 (NM_009546) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AA960166; AL022677; EFP; Zfp147 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_009546 |
| ORF Size | 1902 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR223266).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_009546.2, NP_033572.2 |
| RefSeq Size | 5596 bp |
| RefSeq ORF | 1905 bp |
| Locus ID | 217069 |
| Gene Summary | Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58 and IFIH1. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Mediates 'Lys-63'-linked polyubiquitination of IFIH1. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3.[UniProtKB/Swiss-Prot Function] |
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