Atg4c (NM_175029) Mouse Tagged ORF Clone Lentiviral Particle

CAT＃: MR223616L4V

  • LentiORF®

Lenti ORF particles, Atg4c (GFP-tagged) - Mouse autophagy-related 4C (yeast) (Atg4c), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Datasheet
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CNY 10,070.00

货期*
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规格
    • 200 ul

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经常一起买 (2)
PS100093V
Lenti ORF control particles of pLenti-C-mGFP-P2A-Puro, >1x10^7 TU/ml, 0.5 ml
    • 500 ul

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Specifications

Product Data
Product Name Atg4c (NM_175029) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms Apg4-C; Apg4c; Atg4cl; Autl1
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_175029
ORF Size 1377 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR223616).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_175029.3
RefSeq Size 3236 bp
RefSeq ORF 1377 bp
Locus ID 242557
Gene Summary Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms (By similarity). Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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