Hif1an (NM_176958) Mouse Tagged ORF Clone Lentiviral Particle

CAT＃: MR225292L4V

LentiORF^®

Lenti ORF particles, Hif1an (GFP-tagged) - Mouse hypoxia-inducible factor 1, alpha subunit inhibitor (Hif1an), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Datasheet

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CNY 9,405.00

货期*

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经常一起买 (2)

PS100093V

Lenti ORF control particles of pLenti-C-mGFP-P2A-Puro, >1x10^7 TU/ml, 0.5 ml

CNY 2,950.00

TR30038

One-Wash Lentivirus Titer Kit, HIV-1 p24 ELISA

CNY 5,230.00

Specifications

Product Data
Product Name	Hif1an (NM_176958) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms	2310046M24Rik; A830014H24Rik; FIH; FIH1
Vector	pLenti-C-mGFP-P2A-Puro
ACCN	NM_176958
ORF Size	1047 bp
Sequence Data	ORF Nucleotide Sequence (showhide) The ORF insert of this clone is exactly the same as(MR225292).
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq	NM_176958.3, NP_795932.2
RefSeq Size	6190 bp
RefSeq ORF	1050 bp
Locus ID	319594
Gene Summary	Hydroxylates HIF-1 alpha at 'Asn-799' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins. Also hydroxylates Asp and His residues within ARDs of ANK1 and TNKS2, respectively. Negatively regulates NOTCH1 activity, accelerating myogenic differentiation (By similarity). Positively regulates ASB4 activity, promoting vascular differentiation.[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Product Manuals
TrueORFs: Open Reading Frame Clones - 10 ug in PrecisionShuttle Vector System pLenti-ORF destination vector Transfection - TurboFectin 8.0 Transfection Reagent Plasmid Preparation - PowerPrep Plasmid Purification Kits
FAQs
TrueORF Clones/PrecisionShuttle Organelle Marker Transfection Reagent
SDS
Lenti SDS

Resources

cDNA 克隆相关资源
Video Tutorial: Clone Selection Guide Product Video: What is TrueORF GOLD and why it is the most popular type of clone Video Tutorial: How to make Lentivirus particles Video Tutorial: Is the Lentivirus Safe Product Brochure: cDNA clones $98 Clones. Download the List of 15,000 Protocol: Lentivirus packaging

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