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Ptf1a (NM_018809) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR226228L3V
- LentiORF®
-
Lenti ORF particles, Ptf1a (Myc-DDK-tagged) - Mouse pancreas specific transcription factor, 1a (Ptf1a), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Ptf1a (NM_018809) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | bHLHa29; PTF1-p48; PTF1p48 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_018809 |
| ORF Size | 975 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR226228).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_018809.2, NP_061279.2 |
| RefSeq Size | 1508 bp |
| RefSeq ORF | 975 bp |
| Locus ID | 19213 |
| Gene Summary | Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates.[UniProtKB/Swiss-Prot Function] |
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