Ehmt1 (NM_172545) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR226602L4V

  • LentiORF®

Lenti ORF particles, Ehmt1 (GFP-tagged) - Mouse euchromatic histone methyltransferase 1 (Ehmt1), transcript variant 2, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 20,520.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Ehmt1 (NM_172545) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 9230102N17Rik; D330003E03; Eu-HMTase1; GLP; GLP1; KMT1D; mKIAA1876
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_172545
ORF Size 3867 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR226602).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_172545.3, NP_766133.2
RefSeq Size 5070 bp
RefSeq ORF 3870 bp
Locus ID 77683
Gene Summary Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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