Upf2 (NM_001081132) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR226926L4V

  • LentiORF®

Lenti ORF particles, Upf2 (GFP-tagged) - Mouse UPF2 regulator of nonsense transcripts homolog (yeast) (Upf2), 200ul, >10^7 TU/mL. Note: ORF is codon optimized

ORF Plasmid: DDK tGFP



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CNY 20,235.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Upf2 (NM_001081132) Mouse Tagged ORF Clone Lentiviral Particle
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_001081132
ORF Size 3807 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR226926).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001081132.1, NP_001074601.1
RefSeq Size 5174 bp
RefSeq ORF 3810 bp
Locus ID 326622
Gene Summary Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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