C3IP1 (KLHL12) (NM_021633) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC200894L2V
- LentiORF®
-
Lenti ORF particles, KLHL12 (mGFP-tagged) - Human kelch-like 12 (Drosophila) (KLHL12), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
Product Data | |
Product Name | C3IP1 (KLHL12) (NM_021633) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | C3IP1; DKIR |
Vector | pLenti-C-mGFP |
ACCN | NM_021633 |
ORF Size | 1704 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC200894).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_021633.2 |
RefSeq Size | 3338 bp |
RefSeq ORF | 1707 bp |
Locus ID | 59349 |
Domains | BTB, Kelch |
MW | 63.3 kDa |
Gene Summary | This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
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