Calpain 1 (CAPN1) (NM_005186) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC200964L1V
- LentiORF®
-
Lenti ORF particles, CAPN1 (Myc-DDK tagged) - Human calpain 1, (mu/I) large subunit (CAPN1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 8,930.00
货期*
详询
规格
Cited in 2 publications. |
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经常一起买 (3)
Specifications
Product Data | |
Product Name | Calpain 1 (CAPN1) (NM_005186) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | CANP; CANP1; CANPL1; muCANP; muCL; SPG76 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_005186 |
ORF Size | 2142 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC200964).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_005186.2 |
RefSeq Size | 3110 bp |
RefSeq ORF | 2145 bp |
Locus ID | 823 |
Domains | Calpain_III, EFh |
Protein Families | Druggable Genome, Protease |
Protein Pathways | Alzheimer's disease, Apoptosis |
MW | 81.9 kDa |
Gene Summary | The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy
,null,
Diabetes
,PubMed ID 26470784
[CAPN1]
|
Distinct Roles for ?-Calpain and m-Calpain in Synaptic NMDAR-Mediated Neuroprotection and Extrasynaptic NMDAR-Mediated Neurodegeneration
,null,
The Journal of Neuroscience
,PubMed ID 24285894
[CAPN1]
|
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