Elongin A (TCEB3) (NM_003198) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC202462L4V
- LentiORF®
Lenti ORF particles, TCEB3 (mGFP-tagged) - Human transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) (TCEB3), 200ul, >10^7 TU/mL
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CNY 16,340.00
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Specifications
Product Data | |
Product Name | Elongin A (TCEB3) (NM_003198) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | SIII; SIII p110; TCEB3; TCEB3A |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_003198 |
ORF Size | 2316 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC202462).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_003198.1, NP_003189.1 |
RefSeq Size | 4959 bp |
RefSeq ORF | 2319 bp |
Locus ID | 6924 |
Domains | TFS2N |
Protein Families | Transcription Factors |
MW | 87.2 kDa |
Gene Summary | This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq, Jul 2008] |
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