AIPL1 (NM_014336) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC204079L3V
- LentiORF®
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Lenti ORF particles, AIPL1 (Myc-DDK tagged) - Human aryl hydrocarbon receptor interacting protein-like 1 (AIPL1), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,170.00
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Specifications
Product Data | |
Product Name | AIPL1 (NM_014336) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | AIPL2; LCA4 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_014336 |
ORF Size | 1152 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC204079).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_014336.3 |
RefSeq Size | 2990 bp |
RefSeq ORF | 1155 bp |
Locus ID | 23746 |
Protein Families | Druggable Genome |
MW | 43.9 kDa |
Gene Summary | Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5% of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20% of recessive LCA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
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