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TAX1BP3 (NM_014604) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC204776L1V
- LentiORF®
-
Lenti ORF particles, TAX1BP3 (Myc-DDK tagged) - Human Tax1 (human T-cell leukemia virus type I) binding protein 3 (TAX1BP3), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | TAX1BP3 (NM_014604) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | TIP-1; TIP1 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_014604 |
| ORF Size | 372 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC204776).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014604.2 |
| RefSeq Size | 1398 bp |
| RefSeq ORF | 375 bp |
| Locus ID | 30851 |
| Domains | PDZ |
| MW | 13.7 kDa |
| Gene Summary | This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways; for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017] |
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