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KIFAP3 (NM_014970) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC205208L3V
- LentiORF®
-
Lenti ORF particles, KIFAP3 (Myc-DDK-tagged)-Human kinesin-associated protein 3 (KIFAP3), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,930.00
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| Product Data | |
| Product Name | KIFAP3 (NM_014970) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | dJ190I16.1; FLA3; KAP-1; KAP-3; KAP3; SMAP; Smg-GDS |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_014970 |
| ORF Size | 2376 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC205208).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014970.3 |
| RefSeq Size | 3011 bp |
| RefSeq ORF | 2379 bp |
| Locus ID | 22920 |
| Domains | Armadillo_seg |
| Protein Families | Druggable Genome |
| MW | 91.2 kDa |
| Gene Summary | The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
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