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C6orf57 (SDHAF4) (NM_145267) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC205542L3V
- LentiORF®
-
Lenti ORF particles, SDHAF4 (Myc-DDK tagged) - Human chromosome 6 open reading frame 57 (C6orf57), 200ul, >10^7 TU/mL
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CNY 7,410.00
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规格
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Specifications
| Product Data | |
| Product Name | C6orf57 (SDHAF4) (NM_145267) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | C6orf57; Sdh8 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_145267 |
| ORF Size | 324 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC205542).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_145267.2 |
| RefSeq Size | 526 bp |
| RefSeq ORF | 327 bp |
| Locus ID | 135154 |
| Protein Families | Secreted Protein |
| MW | 12.2 kDa |
| Gene Summary | Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol (PubMed:24954416). Binds to the flavoprotein subunit SDHA in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit SDHB into the SDH catalytic dimer (By similarity).[UniProtKB/Swiss-Prot Function] |
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