B7-2 (CD86) (NM_006889) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC206513L4V
- LentiORF®
Lenti ORF particles, CD86 (mGFP-tagged)-Human CD86 molecule (CD86), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 9,120.00
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Specifications
Product Data | |
Product Name | B7-2 (CD86) (NM_006889) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | B7-2; B7.2; B70; CD28LG2; LAB72 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_006889 |
ORF Size | 969 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC206513).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_006889.4, NP_008820.3 |
RefSeq Size | 2794 bp |
RefSeq ORF | 972 bp |
Locus ID | 942 |
Domains | IGv, IG |
Protein Families | Druggable Genome, Transcription Factors, Transmembrane |
Protein Pathways | Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis |
MW | 37.02 kDa |
Gene Summary | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] |
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