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AMH (NM_000479) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC208397L2V
- LentiORF®
-
Lenti ORF particles, AMH (mGFP-tagged) - Human anti-Mullerian hormone (AMH), 200ul, >10^7 TU/mL
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CNY 9,975.00
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规格
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Specifications
| Product Data | |
| Product Name | AMH (NM_000479) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | MIF; MIS |
| Vector | pLenti-C-mGFP |
| ACCN | NM_000479 |
| ORF Size | 1680 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC208397).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000479.2 |
| RefSeq Size | 2008 bp |
| RefSeq ORF | 1683 bp |
| Locus ID | 268 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway |
| MW | 59.17 kDa |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016] |
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