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BTNL2 (NM_019602) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC214359L2V
- LentiORF®
-
Lenti ORF particles, BTNL2 (mGFP-tagged)-Human butyrophilin-like 2 (MHC class II associated) (BTNL2), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | BTNL2 (NM_019602) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | BTL-II; BTN7; HSBLMHC1; SS2 |
| Vector | pLenti-C-mGFP |
| ACCN | NM_019602 |
| ORF Size | 1365 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC214359).
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| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_019602.1, NP_062548.1 |
| RefSeq Size | 1368 bp |
| RefSeq ORF | 1368 bp |
| Locus ID | 56244 |
| Protein Families | Druggable Genome, Secreted Protein |
| MW | 50.3 kDa |
| Gene Summary | This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. [provided by RefSeq, May 2017] |
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