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Importin 7 (IPO7) (NM_006391) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC215943L4V
- LentiORF®
-
Lenti ORF particles, IPO7 (mGFP-tagged) - Human importin 7 (IPO7), 200ul, >10^7 TU/mL
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CNY 12,540.00
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Specifications
| Product Data | |
| Product Name | Importin 7 (IPO7) (NM_006391) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | Imp7; RANBP7 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_006391 |
| ORF Size | 3114 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC215943).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_006391.1 |
| RefSeq Size | 3557 bp |
| RefSeq ORF | 3117 bp |
| Locus ID | 10527 |
| Domains | IBN_NT |
| Protein Families | Druggable Genome |
| MW | 119.3 kDa |
| Gene Summary | The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. [provided by RefSeq, Jul 2008] |
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