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SMG7 (NM_201568) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC220759L4V
- LentiORF®
-
Lenti ORF particles, SMG7 (mGFP-tagged)-Human Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG7), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 20,900.00
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Specifications
| Product Data | |
| Product Name | SMG7 (NM_201568) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | C1orf16; EST1C; SGA56M |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_201568 |
| ORF Size | 3273 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC220759).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_201568.2 |
| RefSeq Size | 5798 bp |
| RefSeq ORF | 3276 bp |
| Locus ID | 9887 |
| MW | 122 kDa |
| Gene Summary | This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011] |
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