Cytochrome P450 26B (CYP26B1) (NM_019885) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC221075L3V
- LentiORF®
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Lenti ORF particles, CYP26B1 (Myc-DDK-tagged)-Human cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1), 200ul, >10^7 TU/mL
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CNY 9,690.00
Cited in 4 publications. |
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CNY 2,950.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Product Name | Cytochrome P450 26B (CYP26B1) (NM_019885) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | CYP26A2; P450RAI-2; P450RAI2; RHFCA |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_019885 |
ORF Size | 1536 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC221075).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_019885.3, NP_063938.1 |
RefSeq Size | 4567 bp |
RefSeq ORF | 1539 bp |
Locus ID | 56603 |
Protein Families | Druggable Genome, P450 |
Protein Pathways | Retinol metabolism |
MW | 58 kDa |
Gene Summary | This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] |
Citations (4)
The use of this cDNA Clones has been cited in the following citations: |
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Genetic contribution of retinoid related genes to neural tube defects
,null,
Human mutation
,PubMed ID 29297599
[CYP26B1]
|
,null,
The Journal of Pharmacology and Experimental Therapeutics
,PubMed ID 26937021
[CYP26B1]
|
Comparison of the Function and Expression of CYP26A1 and CYP26B1, the two Retinoic Acid Hydroxylases
,null,
Biochemical pharmacology
,PubMed ID 22020119
[CYP26B1]
|
A Comparison of the Roles of Peroxisome Proliferator-Activated Receptor and Retinoic Acid Receptor on CYP26 Regulation
,null,
Molecular Pharmacology
,PubMed ID 19884280
[CYP26B1]
|
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