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TREM2 (NM_018965) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC221132L1V
- LentiORF®
-
Lenti ORF particles, TREM2 (Myc-DDK tagged) - Human triggering receptor expressed on myeloid cells 2 (TREM2), 200ul, >10^7 TU/mL
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CNY 7,410.00
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规格
| Cited in 1 publication. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | TREM2 (NM_018965) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_018965 |
| ORF Size | 690 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC221132).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_018965.1 |
| RefSeq Size | 1041 bp |
| RefSeq ORF | 693 bp |
| Locus ID | 54209 |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| MW | 23.4 kDa |
| Gene Summary | This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation
,null,
The Journal of Biological Chemistry
,PubMed ID 33823153
[TREM2]
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