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LBP (NM_004139) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC221961L1V
- LentiORF®
-
Lenti ORF particles, LBP (Myc-DDK tagged) - Human lipopolysaccharide binding protein (LBP), 200ul, >10^7 TU/mL
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CNY 9,310.00
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Specifications
| Product Data | |
| Product Name | LBP (NM_004139) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | BPIFD2 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_004139 |
| ORF Size | 1443 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC221961).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_004139.2 |
| RefSeq Size | 1823 bp |
| RefSeq ORF | 1446 bp |
| Locus ID | 3929 |
| Domains | BPI1 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Toll-like receptor signaling pathway |
| MW | 53.38 kDa |
| Gene Summary | The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012] |
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