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NXF1 (NM_001081491) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC222620L3V
- LentiORF®
-
Lenti ORF particles, NXF1 (Myc-DDK tagged) - Human nuclear RNA export factor 1 (NXF1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 7,885.00
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Specifications
| Product Data | |
| Product Name | NXF1 (NM_001081491) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | MEX67; TAP |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001081491 |
| ORF Size | 1068 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC222620).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001081491.1 |
| RefSeq Size | 4147 bp |
| RefSeq ORF | 1071 bp |
| Locus ID | 10482 |
| MW | 40.5 kDa |
| Gene Summary | This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
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