LDB3 (NM_001080116) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC223167L4V
- LentiORF®
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Lenti ORF particles, LDB3 (mGFP-tagged) - Human LIM domain binding 3 (LDB3), transcript variant 4, 200ul, >10^7 TU/mL
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CNY 9,120.00
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规格
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Specifications
Product Data | |
Product Name | LDB3 (NM_001080116) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | CMD1C; CMH24; CMPD3; CYPHER; LDB3Z1; LDB3Z4; LVNC3; MFM4; ORACLE; PDLIM6; ZASP |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001080116 |
ORF Size | 849 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC223167).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001080116.1, NP_001073585.1 |
RefSeq Size | 1659 bp |
RefSeq ORF | 852 bp |
Locus ID | 11155 |
MW | 30.8 kDa |
Gene Summary | This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq, Jan 2010] |
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