NKIRAS2 (NM_001144928) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC226756L3V
- LentiORF®
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Lenti ORF particles, NKIRAS2 (Myc-DDK-tagged)-Human NFKB inhibitor interacting Ras-like 2 (NKIRAS2), transcript variant 4, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | NKIRAS2 (NM_001144928) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | kappaB-Ras2; KBRAS2 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001144928 |
ORF Size | 405 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC226756).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001144928.1 |
RefSeq ORF | 408 bp |
Locus ID | 28511 |
MW | 14.7 kDa |
Gene Summary | Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity).[UniProtKB/Swiss-Prot Function] |
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