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Collagen XI alpha 2 (COL11A2) (NM_001163771) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC228226L3V
- LentiORF®
-
Lenti ORF particles, COL11A2 (Myc-DDK tagged) - Human collagen, type XI, alpha 2 (COL11A2), transcript variant 4, 200ul, >10^7 TU/mL
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CNY 8,170.00
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Specifications
| Product Data | |
| Product Name | Collagen XI alpha 2 (COL11A2) (NM_001163771) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001163771 |
| ORF Size | 870 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC228226).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001163771.1 |
| RefSeq ORF | 873 bp |
| Locus ID | 1302 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ECM-receptor interaction, Focal adhesion |
| MW | 31.96 kDa |
| Gene Summary | This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6. [provided by RefSeq, Jul 2009] |
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