p53R2 (RRM2B) (NM_001172478) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC229848L4V
- LentiORF®
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Lenti ORF particles, RRM2B (mGFP-tagged) - Human ribonucleotide reductase M2 B (TP53 inducible) (RRM2B), transcript variant 3, 200ul, >10^7 TU/mL
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CNY 9,120.00
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Specifications
Product Data | |
Product Name | p53R2 (RRM2B) (NM_001172478) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | MTDPS8A; MTDPS8B; P53R2 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001172478 |
ORF Size | 897 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC229848).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001172478.1 |
RefSeq ORF | 900 bp |
Locus ID | 50484 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Glutathione metabolism, Metabolic pathways, p53 signaling pathway, Purine metabolism, Pyrimidine metabolism |
MW | 35 kDa |
Gene Summary | This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010] |
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