Sptlc1 (NM_001108406) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR201484L4V

  • LentiORF®

Lenti ORF particles, Sptlc1 (GFP-tagged ORF) - Rat serine palmitoyltransferase, long chain base subunit 1 (Sptlc1), 200ul, >10^7 TU/mL



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CNY 10,260.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Sptlc1 (NM_001108406) Rat Tagged ORF Clone Lentiviral Particle
Synonyms Lcb1; RGD1306617; Spt1
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_001108406
ORF Size 1419 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RR201484).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001108406.1, NP_001101876.1
RefSeq Size 3034 bp
RefSeq ORF 1422 bp
Locus ID 361213
Gene Summary Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference (By similarity). Required for adipocyte cell viability and metabolic homeostasis (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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