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Srgap2 (NM_001134958) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR207887L3V
- LentiORF®
-
Lenti ORF particles, Srgap2 (Myc-DDK-tagged ORF) - Rat SLIT-ROBO Rho GTPase activating protein 2 (Srgap2), 200ul, >10^7 TU/mL
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CNY 13,595.00
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Specifications
| Product Data | |
| Product Name | Srgap2 (NM_001134958) Rat Tagged ORF Clone Lentiviral Particle |
| Synonyms | RGD1566016 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001134958 |
| ORF Size | 2574 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR207887).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001134958.1, NP_001128430.1 |
| RefSeq Size | 3559 bp |
| RefSeq ORF | 2577 bp |
| Locus ID | 360840 |
| Gene Summary | RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral cortex. May play a role for cognition, learning and memory. In non-neuronal cells, it may also play a role in cell migration by regulating the formation of lamellipodia and filopodia (By similarity).[UniProtKB/Swiss-Prot Function] |
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