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Fer (NM_001106928) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR208624L3V
- LentiORF®
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Lenti ORF particles, Fert2 (Myc-DDK-tagged ORF) - Rat fer (fms/fps related) protein kinase, testis specific 2 (Fert2), 200ul, >10^7 TU/mL
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CNY 8,978.00
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Specifications
| Product Data | |
| Product Name | Fer (NM_001106928) Rat Tagged ORF Clone Lentiviral Particle |
| Synonyms | Fert2; Flk; Flk_retired |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001106928 |
| ORF Size | 1359 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR208624).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001106928.1, NP_001100398.1 |
| RefSeq Size | 3387 bp |
| RefSeq ORF | 1362 bp |
| Locus ID | 301737 |
| Gene Summary | Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide (LPS). Plays a role in neuronal cell death after brain damage. Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11. May phosphorylate JUP and PTPN1. Can phosphorylate STAT3, but the biological relevance of this clearly depends on cell type and stimulus (By similarity). Plays a role in synapse organization, trafficking of synaptic vesicles, the generation of excitatory postsynaptic currents and neuron-neuron synaptic transmission.[UniProtKB/Swiss-Prot Function] |
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